Abstract

Case Report

The Need of Wider and Deeper Skin Biopsy in Verrucous Carcinoma of the Sole

Luca Damiani*, Giuseppe Argenziano, Andrea Ronchi, Francesca Pagliuca, Emma Carraturo, Vincenzo Piccolo and Gabriella Brancaccio

Published: 31 January, 2025 | Volume 9 - Issue 1 | Pages: 005-007

Verrucous carcinoma is a rare, slow-growing squamous cell carcinoma that can occur in acral regions, including the plantar surface, being named carcinoma cuniculatum. The tumor presents as a well-demarcated, exudative lesion, resembling benign conditions like warts or infections. In this case, a verrucous lesion on the left plantar surface initially appeared to be non-malignant, with multiple incisional biopsies showing only inflammation. A final excisional biopsy of a large part of it confirmed the initial suspicion of malignancy, prompting complete excision and appropriate management. This case underscores the importance of performing wide and deep biopsies for early diagnosis and timely treatment of a suspected verrucous carcinoma.

Read Full Article HTML DOI: 10.29328/journal.adr.1001036 Cite this Article Read Full Article PDF

Keywords:

Carcinoma; Verrucous; Cutaneous; Foot; Cuniculatum; Biopsy; Diagnosis

References

  1. Saurat JH, LD, TL. Dermatology and Sexually Transmitted Infection. 6th ed. Paris: Edra; 2018.
  2. Fawaz B, Vieira C, Decker A, Lawrence N. Surgical treatment of verrucous carcinoma: a review. J Dermatolog Treat. 2022;33(4):1811-1815. Available from: https://doi.org/10.1080/09546634.2021.1914312
  3. Nagarajan D, Chandrasekhar M, Jebakumar J, Menon KA. Verrucous carcinoma of foot at an unusual site: lessons to be learnt. South Asian J Cancer. 2017;6(2):63. Available from: https://doi.org/10.4103/2278-330x.208839
  4. Chauhan K, Jassal V, Sara GK, Bansal V, Hatwal V. Histopathological study of verrucous lesions and its mimics. J Microsc Ultrastruct. 2021;9(2):86-97. Available from: https://doi.org/10.4103/jmau.jmau_47_19
  5. Di Palma V, Stone JP, Schell A, Dawes JC. Mistaken diabetic ulcers: A case of bilateral foot verrucous carcinoma. Case Rep Dermatol Med. 2018;2018:4192657. Available from: https://doi.org/10.1155/2018/4192657
  6. Ye Q, Hu L, Jia M, Deng LJ, Fang S. Cutaneous verrucous carcinoma: a clinicopathological study of 21 cases with long-term clinical follow-up. Front Oncol. 2022;12:953932. Available from: https://doi.org/10.3389/fonc.2022.953932
  7. Farag AF, Abou-Alnour DA, Abu-Taleb NS. Oral carcinoma cuniculatum, an unacquainted variant of oral squamous cell carcinoma: a systematic review. Imaging Sci Dent. 2018;48(4):233-244. Available from: https://doi.org/10.5624/isd.2018.48.4.233
  8. Shwe Daniel S, Cox SV, Kraus CN, Elsensohn AN. Epithelioma cuniculatum (plantar verrucous carcinoma): a systematic review of treatment options. Cutis. 2023;111(2):E19-E24. Available from: https://doi.org/10.12788/cutis.0720
  9. Fawaz B, Vieira C, Decker A, Lawrence N. Surgical treatment of verrucous carcinoma: a review. J Dermatolog Treat. 2022;33(4):1811-1815. Available from: https://doi.org/10.1080/09546634.2021.1914312
  10. Nunes-Abreu F, Hidalgo-Caro R, Lorda-Barraguer E, Cristóbal-Redondo V, Céspedes-Guirao FJ. Consider carcinoma cuniculatum in recurrent foot ulcer: a case report and literature review. Arch Plast Surg. 2024;51(6):575-580. Available from: https://doi.org/10.1055/a-2316-3824

Figures:

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